Cov kws tshawb fawb los ntawm Queen Mary University hauv London tau ua ib qho kev soj ntsuam tshiab ntawm kev sim cov ntaub ntawv ntawm cov neeg haus luam yeeb cev xeeb tub thiab pom tias nquag siv cov tshuaj nicotine hloov thaum cev xeeb tub tsis cuam tshuam nrog cov xwm txheej tsis zoo ntawm cev xeeb tub lossis cov txiaj ntsig.
Txoj kev tshawb no, luam tawm hnub no nyob rau hauv Phau Ntawv Xov Xwm ntawm Kev Txhaum Cai, tau ua ib qho kev ntsuam xyuas thib ob ntawm kev sim cev xeeb tub (PREP) randomized tswj kev sim ntawm e-luam yeeb thiab thaj ua rau thaj. Txoj kev tshawb no tsom xyuas kev nyab xeeb ntawm e-luam yeeb (EC) thiab nicotine thaj ua rau thaj (NRT) hauv kev pab cov neeg haus luam yeeb cev xeeb tub txiav luam yeeb. Cov neeg koom nrog suav nrog 1140 tus neeg haus luam yeeb cev xeeb tub, nrog rau kev ntsuas suav nrog kev noj tshuaj nicotine piv rau cov hauv paus, qhov hnyav thaum yug, lwm yam kev xeeb tub, cov xwm txheej tsis zoo, cov tsos mob ua pa ntawm niam txiv, thiab rov qab los ntawm cov neeg haus luam yeeb thaum ntxov.
Cov txiaj ntsig kev tshawb fawb qhia tau tias nquag siv e-luam yeeb lossis nicotine thaj ua rau thaj los ntawm cov neeg haus luam yeeb cev xeeb tub zoo li tsis muaj feem cuam tshuam rau qhov tshwm sim tsis zoo. Tshwj xeeb, kev siv EC muaj ntau dua li kev siv NRT, thiab cov poj niam uas tsis haus luam yeeb thaum cev xeeb tub (EOP) thiab siv EC muaj 45% txo qis hauv salivary cotinine. Tsis tas li ntawd, tsis muaj qhov sib txawv ntawm qhov hnyav thaum yug me nyuam ntawm cov neeg haus luam yeeb thiab cov neeg haus luam yeeb uas siv cov khoom nicotine, qhia tias kev siv EC thiab NRT thaum cev xeeb tub lig yuav tsis cuam tshuam rau kev loj hlob ntawm lub cev.
Tsis tas li ntawd, kev tshawb fawb tau pom tias kev siv cov khoom nicotine thaum cev xeeb tub tsis ua rau muaj kev pheej hmoo ntawm kev rov qab los ntawm kev txiav tawm ntxov. Tsis tas li ntawd, kev soj ntsuam ntawm qhov tshwm sim ntawm yug thiab leej niam, cov xwm txheej tsis zoo, thiab tus nqi rov tshwm sim tau raug kho raws li cov yam ntxwv hauv paus cuam tshuam nrog cov txiaj ntsig, thiab tsis muaj qhov sib txawv tseem ceeb ntawm cov neeg koom siv cov khoom siv nicotine thiab cov tsis siv nicotine.
Nws yog tsim nyog sau cia tias qhov kev ntsuam xyuas ntawm cov tsos mob ua pa qhia tau hais tias kev txhim kho ntawm hnoos thiab phlegm nyob rau hauv EC cov neeg siv yog siab tshaj qhov uas tsis yog cov neeg siv, thiab tsis muaj kev hloov nyob rau hauv ua tsis taus pa thiab hawb pob. Txoj kev tshawb no kuj tau txheeb xyuas cov kev hloov pauv hauv qib cotinine hauv salivary thiab pom tias kev siv cov khoom nicotine nquag cuam tshuam nrog kev hloov pauv hauv cotinine qib. Piv nrog rau cov neeg txiav luam yeeb thiab cov neeg haus luam yeeb, ob tus neeg siv thiab cov neeg haus luam yeeb tau nthuav tawm cov qauv sib txawv ntawm cotinine nce. Txawm li cas los xij, txoj kev tshawb fawb lees paub qee qhov kev txwv, xws li kev tshaj tawm tus kheej tsis txaus ntseeg thiab muaj peev xwm txheeb xyuas tau tsawg hauv qee qhov kev sib piv vim qhov me me piv txwv.
Hauv cov ntsiab lus, cov kev tshawb fawb tau pom tias nquag siv e-luam yeeb lossis nicotine thaj tsam los ntawm cov neeg haus luam yeeb cev xeeb tub zoo li tsis cuam tshuam rau qhov tshwm sim tsis zoo.
Qhov kev tshawb pom no muab kev nkag siab tseem ceeb rau kev nyab xeeb ntawm cov khoom nicotine raws li kev haus luam yeeb ntxiv thaum cev xeeb tub, thiab cov ntaub ntawv tseem ceeb rau cov kws kho mob thiab cov poj niam cev xeeb tub nrhiav kev txhawb nqa kev haus luam yeeb.